Regulation of adenylyl cyclase in LTP
Identifieur interne : 000C69 ( Main/Exploration ); précédent : 000C68; suivant : 000C70Regulation of adenylyl cyclase in LTP
Auteurs : Erik D. Roberson [États-Unis] ; J. David Sweatt [États-Unis]Source :
- Behavioral and Brain Sciences [ 0140-525X ] ; 1995-09.
Abstract
Our results on hippocampal long-term potentiation are considered in the context of Xia et al.'s hypothesis. Whereas the target article proposes presynaptic PKC involvement in adenylyl cyclase activation by phosphorylation of nenromodulin, we suggest an additional postsynaptic role involving RC3/nenrogranin. Finally, we examine the possibility that the adenylyl cyclase mutant mouse may display normal learning with a selective impairment of memory.
Url:
DOI: 10.1017/S0140525X0003942X
Affiliations:
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